BIOLOGY HIGH SCHOOL

Why are polygenic diseases less suited to gene therapy?

Answers

Answer 1
Answer:

Answer:

Polygenic therapies are more likely to show unintended effects in other regions of the genome likely resulting in harmful diseases.

Explanation:

Gene therapy involves biotechnological techniques that add or remove gene sequences in the genome. These are typically used in eliminating harmful genes that cause genetic diseases or disorders and are generally thought to improve an individual's quality of life.

Polygenic traits are controlled by several genes. Similarly, polygenic diseases may be caused by variations in several gene sequences. These include hypertension, heart disease, and diabetes. Polygenic therapies are more likely to show unintended effects in other regions of the genome, leading to other deleterious disease-causing effects.

Related Questions

Which of the following is not evidence supporting the tectonic plate theory?Coal has been found under Antarctica. Some continental coastlines fit together like puzzle pieces. Glacier evidence has been found in continents that used to be attached to Antarctica. Fossils of sea creatures have been found on land thousands of miles from any ocean.
If a plant's leaves increased in surface area, which of the following would not happen?Select one:a. The plant would be able to absorb more sunlight.b. The plant may lose water too quickly.c. The plant may increase the rate of photosynthesis.d. The plant will draw water up more slowly.
1. Digital signals carry less information per second.2. Information can be stored for future recovery.3. Digital signals can be transmitted over long distances.4. Signal loss happens less frequently.Which features are correct?
What is the role of ATP in the cell?a. transport energyb. drive photosynthesis c. maintain homeostasis d. initiate cellular respiration
Where does the subtrate bind to the enzyme

Freshwater protists with two flagella that can be photosynthetic or heterotrophic are calledA. amoebas.
B. ciliates.
C. dinoflagellates.
D. euglenoids.

Answers

The correct answer should be euglenoids. This means that they can both produce food on their own using sun because they have chloroplasts and do photosynthesis, and they can feed on food produced by others if need be or if there's no exposure to sunlight. They are also known as Euglena and are very recognizable due to the whip that they have.

Tại sao con người chúng ta lại sốt nhiều lần như vậy?

Answers

Answer:

Fever is an elevated temperature of the human body that is substantially beyond the normal range. Normal body temperature fluctuates daily from about one degree below 98.6 degrees Fahrenheit to one degree above that number. Lower body temperatures usually occur before dawn; higher temperatures in the afternoon.

Body temperature also varies slightly depending on where on the human body it is measured. Rectal (internal) temperature tends normally to be higher than skin (surface) temperature. Oral and armpit temperatures can approximate actual body temperature and are more convenient to measure.

What is an atom’s atomic number? the number of electrons in an atom the number of neutrons in an atom the number of protons in an atom the number of bonds in an atom

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Answer:

the number of protons in an atom

Explanation:

edge2020

Answer:the number of electrons in an atom the number of neutrons in an atom the number of protons in an atom the number of bonds in an atom

Explanation:

Why will a saltwater fish not survive in a freshwater aquarium due to osmosis? A) The fish will not be able to regulate its internal salt concentration in a freshwater environment. B) The fish will experience excessive water intake, leading to cell swelling and potential bursting. C) The fish will lose essential electrolytes and minerals through osmosis, causing imbalances in its body. D) All of the above.

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Answer:

D) All of the above.

Explanation:

All of these things can happen to a saltwater fish living in a freshwater aquarium.

How can vaccinations prevent the onset of certain diseases or disorders? a) Vaccinations build up the body's hormonal balances. b) Vaccinations build up the body's ability to fight illnesses. c) Vaccinations build up the body's ability to cure tumors. d) Vaccinations build up the body's sensitivity to medications.

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Answer:

B)

Explanation:

Vaccinations build the body's ability to fight illnesses by introducing a de-activated virus to the body, which then produces antibodies that can kill the virus. The immune system can then "remember" the viruses' structure for future encounters.

What stomach secretion is necessary for normal hemoglobin production in RBCs?A. HCl
B. pepsinogen
C. intrinsic factor
D. gastric lipase

Answers

Instrinsic factor is the stomach secretion necessary for normal hemoglobin production in RBCs.
Other Questions
Which of the following plant cell structures could not be seen when using the 10X objective of the compound microscope?A) Nucleus2) Cell wall3) Cytoplasm4) Endoplasmic Reticulum
Angiosperms do not need water for fertilization. Why?
Why is it important to sequence your plasmid after purifying it?
If an outdoor runner develops a headache, feels tired, and has an elevated heart rate, what is the most probable cause?A. Insufficient caloriesB. OverhydrationC. DehydrationD. Lack of protein