: a pediatric fellow in your clinical practice group has identified a new clinical isolate of the gram-positive staphylococcus epidermidis that expresses a high level of an abc-type multidrug resistance (mdr) efflux pump. which of the following antibiotics would be the best choice for treating an infection caused by this bacterial strain? you may assume that the mdr efflux pump is its only resistance mechanism. all of the listed antibiotics would work well to treat ordinary staphylococcus epidermidis infections. choose one: a. rifampin b. tetracycline c. vancomycin d. sulfanilamide e. any of the antibiotics listed above would be effective choices. f. none of the antibiotics listed above would be effective choices.

Answers

Answer 1

Answer:

None of the antibiotics indexed above could be a suitable pick for treating an infection due to the bacterial strain described.

The gram-positive staphylococcus epidermidis that expresses a excessive degree of an ABC-type multidrug resistance (MDR) efflux pump is probably resistant to all the antibiotics indexed.

Rifampin, tetracycline, vancomycin, and sulfanilamide are all probable to be ineffective in this case because of its MDR efflux pump, which permits it to pump out those antibiotics and decrease their effectiveness.

In general, the best option for treating an infection due to a bacterial pressure with an MDR efflux pump could be an antibiotic that is not affected by the pump. Some alternatives for treating MDR infections encompass polymyxins (including colistin), tigecycline, and Fosfomycin.

However, the unique antibiotic that might be the best option for treating an infection due to this bacterial pressure could rely on the specifics of the contamination, including the area of the contamination and the patient's typical health. It is crucial to work with a healthcare professional to decide the most suitable remedy for an infection with an MDR bacterial strain.

Read more about multidrug resistance at:

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I hope it helps, Regards.

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