B.Millions of American Indians died of disease.
C.Horses and cattle went from Africa to Europe.
D.Potatoes and tomatoes were introduced in the Americas.
The correct answer is B. Millions of American Indians died during the Columbian Exchange, due to the fact that the food and animals that entered into America from Europe generated diseases because they did not have the necessary antibodies to consume them. For example, almost 30% of the American Indians died from smallpox a few years after the Europeans started to bring their products to the continent.
After Muhammad's death, the expansion of Islam began and the unification of Arab tribes, by forming caliphates headed by religious leaders, caliphs, which began the spread of the Islamic territory. This also meant acquiring territories that were not completely Arabian. It should be kept in mind that Persia, the successor to the ancient Mesopotamia, and as such, largely contained the territory of ancient Mesopotamia, although not all. Thus, 25 years after Muhammad's death, the territories acquired included parts of Persia, Mesopotamia and Egypt.