The glomerular lesion that is characterized by thickening of the glomerular capillary wall with immune deposition is called membranous glomerulonephritis.
In this condition, there is a buildup of immune complexes, which are composed of antibodies and antigens, in the glomerular capillary walls. This immune deposition leads to inflammation and thickening of the walls, impairing the filtration function of the kidneys.
The thickening of the glomerular capillary wall in membranous glomerulonephritis is caused by the accumulation of immune complexes in the subepithelial space. These immune complexes can be formed due to various underlying causes, such as autoimmune diseases, infections, medications, or certain cancers. The immune complexes trigger an inflammatory response, attracting immune cells to the glomerular capillary walls and causing damage.
As a result of the thickening of the glomerular capillary wall, the normal filtration process in the kidneys is disrupted. This can lead to proteinuria (presence of excess protein in the urine), hypoalbuminemia (low levels of albumin in the blood), and edema (swelling) in the affected individual. Over time, the chronic inflammation and scarring can further impair kidney function and may progress to chronic kidney disease.
To diagnose membranous glomerulonephritis, a kidney biopsy is typically performed to examine the glomeruli under a microscope. The presence of thickened glomerular capillary walls with immune deposits confirms the diagnosis.
Treatment for membranous glomerulonephritis aims to reduce inflammation, control symptoms, and preserve kidney function. Depending on the underlying cause and severity of the condition, treatment options may include medications such as immunosuppressants, angiotensin-converting enzyme inhibitors (ACE inhibitors), or angiotensin receptor blockers (ARBs). In some cases, individuals may require supportive measures such as dietary modifications and fluid restriction.
In summary, membranous glomerulonephritis is a glomerular lesion characterized by thickening of the glomerular capillary wall due to immune deposition. It can result in kidney dysfunction and is typically diagnosed through a kidney biopsy. Treatment options focus on reducing inflammation and preserving kidney function.
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In the nucleus, DNA wraps around proteins called histones to form structures known as nucleosomes which further condense into chromosomes during cell division.
In the nucleus of eukaryotes, the DNA is wrapped around proteins called histones to form structures known as nucleosomes. These nucleosomes are likened to 'beads on a string' where the 'beads' are the histone proteins with DNA wrapped around them, and the 'string' is the DNA linking each nucleosome. These nucleosomes further condense into a 30 nm fiber and eventually form the tightly compacted structure of a chromosome, particularly during the metaphase stage of cell division.
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Explanation:
Pigmentation is the coloring of a person's skin. When a person is healthy, their skin color will appear normal. In the case of illness or injury, the person's skin may change color, becoming darker (hyperpigmentation) or lighter (hypopigmentation).
b. glucose
c. lipids
d. mannos
Answer:
B Glucose
Explanation: