Which of the following statements about the cell cycle is/are correct? Choose all that apply. Which of the following statements about the cell cycle is/are correct? Choose all that apply. The cell cycle consists of 5 distinct phases: I, M, G1, S, and G2. All preparation for cell division occurs during M phase. At any stage of mitosis, a cell has twice as much DNA as in G1. Metabolically active cells can exit, and sometimes re-enter, the cell cycle. Extracellular conditions have no effect on cell cycle progression. Once the cell cycle has begun, it cannot be stopped without resulting in cell death.

Answer: The correct statements are-

1. At any stage of mitosis a cell has twice as much as DNA in G1.

2. Metabolically active cells can exit, and sometimes re-enter, the cell cycle.

Explanation :

1.. The cell cycle consists of 4 distinct phases - M phase which is the mitotic phase and the G1, S and G2 phase which together form the interphase. The interphase is preparatory phase wherein the cell grows in size, replicates the DNA etc. whereas the M phase is the one where events related to cell division takes place.

2. The cell has 2C amount of DNA during G1 but since the DNA replication takes place during S phase, the amount of DNA doubles up to 4 C and remains so in G2 and M phase until cytokinesis results in the formation of 2 daughter cells.

3. Sometimes, the metabolically active cells can exit the cell cycle and become quiescent until the conditions are favourable. When these quiescent cells recieve the right stimulus they can re enter the cell cycle.

4. Extracellular conditions such as nutrient availability, presence of certain mitogens, growth factors etc. do regulate the cell cycle progression. If any of these extracellular facotrs are limiting the cell cycle is arrested.

5. Once the cell cycle starts, it can be stopped without leading to cell death. When this happens it is known as cell cycle arrest. During this arrest several factors are assessed and if theire is need for repair of DNA then that also takes place. Once, the limitations are overcome or the repair is done, the cell cycle can then continue.

Final answer:

The cell cycle, comprising of interphase (G₁, S, G₂ stages) and the mitotic phase, is a series of regulated events leading to cell division. This cycle can be influenced by internal and external conditions.

Explanation:

The cell cycle is a carefully regulated sequence involving cell growth, DNA replication, and cell division that results in two new daughter cells. The cycle comprises two main phases: interphase and the mitotic phase.

Interphase is further divided into three stages: G₁, S, and G₂. During G₁, the cell is active at the biochemical level, accumulating the building blocks of chromosomal DNA, associated proteins and energy reserves.

The S phase is marked by DNA replication, resulting in identical pairs of DNA molecules. The G₂ phase is another period of growth and preparation for division. The mitotic phase includes karyokinesis (mitosis) and cytokinesis, leading to the separation of cytoplasmic components of daughter cells.

It's worth note that metabolically active cells can indeed exit and re-enter the cell cycle, and extracellular conditions along with internal signals can influence the progression of the cell cycle.

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