Answer:
F
Explanation:
E2020
Answer:
Direct observation of evolutionary change: creation of drug-resistant bacteria.
Fossil record: discovery of transitional forms of animals, discovery of shells of extinct organisms
Homology: similarities in mammalian forelimbs, identical genetic code in fireflies and tobacco plants, vestigial pelvis in right whales
Biogeography: resemblance of endangered island species to neighboring mainland species,
Direct Observation of Evolution:
Direct observation of evolution involves studying the changes in a population over a relatively short period of time. One example of direct observation is the development of antibiotic resistance in bacteria.
Scientists have observed that certain strains of bacteria can evolve resistance to antibiotics through genetic mutations and natural selection. By exposing bacteria to antibiotics in laboratory experiments, researchers can directly observe the process of evolution as the bacteria adapt and survive in the presence of the drugs.
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Answer:
An enzyme is a protein. Any change in the primary structure of a protein (the primary structure is the aminoacid sequence) can induce a change in the secondary, as well as tertiary structure (tridimensional conformation). This change in the shape of the enzyme can affect its activity, since it can change the active site consequently to this conformational change.
Explanation:
B. Mismatch repair
C. Direct repair by methyltransferases
D. Nucleotide excision repair
Answer:
The correct answer is B. Mismatch repair
Explanation:
Mismatch repair pathway recognizes the mismatched base pair that incorporated during DNA replication and then excise that incorrect base. After excision, it repairs the DNA.
The mismatched daughter strand is distinguished from the parent strand by mismatch repair system as the parent strand is methylated at some bases but the daughter strand is not methylated.
Three proteins help in mismatch repair MutH, MutL, MutS. Mut H and Mut S recognize the mismatch, Mut H excise the unmethylated strand from 5' side. Then helicase and exonuclease enzymes clave the segment from cleavage site to beyond the mismatch base.
The gap created by this action is filled by DNA polymerase and sealed by enzyme DNA ligase.
The 'Mismatch repair' pathway corrects mistakes when an incorrect nucleotide has been incorporated into a DNA sequence and DNA polymerase fails to recognize it. This pathway involves several proteins that recognize the error, excise the incorrect sequence, and re-synthesize the correct sequence.
When DNA polymerase fails to recognize that an incorrect nucleotide has been incorporated, resulting in a mismatch, the Mismatch repair pathway is in charge to correct this mistake. This system detects and repairs erroneous insertion, deletion, and mis-incorporation of bases that can arise during DNA replication and recombination, as well as repairing some forms of DNA damage. This process involves several proteins including MutS, MutL, and MutH. They recognize the error, excise the incorrect sequence and then re-synthesize the correct sequence using the original undamaged DNA strand as a template. The 'Mismatch repair' is a crucial mechanism to maintain the integrity of genetic information.
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